Epilepsy in Down syndrome—prevalence in three age groups

A prevalence study of epilepsy in patients with Down syndrome (n = 85) in three age-groups (14-16 years, 23-29 years, 50-60 years) was conducted in the county of Aarhus, Denmark. Seventy-two patients (85%) participated. An interview and a neurological examination were performed. An EEG was recorded in 50 patients. Twelve patients (17%) had epilepsy. ILAE-1981-classification: two with partial seizures, seven with primary generalized and three with unclassifiable generalized seizures. Two patients with epilepsy had a normal EEG and 13 patients without epilepsy had an abnormal EEG.